La realizzazione della sede del TIFPA

In questa nota è illustrata l'attività svolta durante il primo anno di effettiva operatività del TIFPA allo scopo di realizzare un progetto per la ristrutturazione degli spazi da destinare a sede del Centro, all'interno dell'edificio di proprietà dell'Università degli Studi di Trento che ospita le attività del Dipartimento di Fisica. Vengono descritte le successive fasi di evoluzione del progetto, da quelle iniziali di definizione delle linee guida generali, fino alle attività conclusive di allestimento dei locali e dei laboratori

I Servizi Informatici del TIFPA

In questa nota sono descritti i servizi informatici del TIFPA. Viene fornita una panoramica della peculiare situazione in cui i servizi sono stati sviluppati, vengono descritte le sinergie attuate con i servizi informatici dell'Università di Trento, sono analizzate le soluzioni in cui l'interazione con l'Università si è rivelata la scelta migliore e quelle in cui la scelta più adeguata è stata una gestione autonoma del servizio

A General Organocatalytic System for Electron Donor-Acceptor Complex Photoactivation and Its Use in Radical Processes

We report herein a modular class of organic catalysts that, acting as donors, can readily form photoactive electron donor-acceptor (EDA) complexes with a variety of radical precursors. Excitation with visible light generates open-shell intermediates under mild conditions, including nonstabilized carbon radicals and nitrogen-centered radicals. The modular nature of the commercially available xanthogenate and dithiocarbamate anion organocatalysts offers a versatile EDA complex catalytic platform for developing mechanistically distinct radical reactions, encompassing redox-neutral and net-reductive processes. Mechanistic investigations, by means of quantum yield determination, established that a closed catalytic cycle is operational for all of the developed radical processes, highlighting the ability of the organic catalysts to turn over and iteratively drive every catalytic cycle. We also demonstrate how the catalysts' stability and the method's high functional group tolerance could be advantageous for the direct radical functionalization of abundant functional groups, including aliphatic carboxylic acids and amines, and for applications in the late-stage elaboration of biorelevant compounds and enantioselective radical catalysis

Difficult diagnosis of angiomatoid fibrous histiocytoma of the leg mimicking a benign condition

Angiomatoid fibrous histiocytoma is a rarely metastasizing soft-tissue tumor of low-grade malignancy. Here we report a case of angiomatoid fibrous histiocytoma located in the leg of a 15-year-old female. This case is of particular interest due to its radiological features that led to raise two questions concerning the nature of the disease (is it reactive or tumoral?) and its site of origin (within soft tissues or the tibial periosteum?). Here we describe ultrasound, magnetic resonance imaging, computed tomography scan and positron emission tomography findings that helped answer these questions, understand the real nature of the disease and its appropriate treatment. This case shows that a single type of imaging technique may not be sufficient to understand the real nature of a musculoskeletal lesion and that it is necessary to combine all information derived from various imaging techniques in order to correctly diagnose and treat the disease

A Photochemical Organocatalytic Strategy for the α-Alkylation of Ketones by using Radicals

Reported herein is a visible-light-mediated radical approach to the α-alkylation of ketones. This method exploits the ability of a nucleophilic organocatalyst to generate radicals upon SN2-based activation of alkyl halides and blue light irradiation. The resulting open-shell intermediates are then intercepted by weakly nucleophilic silyl enol ethers, which would be unable to directly attack the alkyl halides through a traditional two-electron path. The mild reaction conditions allowed functionalization of the α position of ketones with functional groups that are not compatible with classical anionic strategies. In addition, the redox-neutral nature of this process makes it compatible with a cinchona-based primary amine catalyst, which was used to develop a rare example of enantioselective organocatalytic radical α-alkylation of ketones

Spondylocarpotarsal synostosis syndrome: \u201cBat wings\u201d spinal fusions and \u201cladybug\u201d carpal coalitions

No abstract availabl

Craniofacial osteomas: From diagnosis to therapy

An osteoma is a benign bone lesion with no clear pathogenesis, almost exclusive to the craniofacial area. Osteomas show very slow continuous growth, even in adulthood, unlike other bony lesions. Since these lesions are frequently asymptomatic, the diagnosis is usually made by plain radiography or by a computed tomography (CT) scan performed for other reasons. Rarely, the extensive growth could determine aesthetic or functional problems that vary according to different locations. Radiographically, osteomas appear as radiopaque lesions similar to bone cortex, and may determine bone expansion. Cone beam CT is the optimal imaging modality for assessing the relationship between osteomas and adjacent structures, and for surgical planning. The differential diagnosis includes several inflammatory and tumoral pathologies, but the typical craniofacial location may aid in the diagnosis. Due to the benign nature of osteomas, surgical treatment is limited to symptomatic lesions. Radical surgical resection is the gold standard therapy; it is based on a minimally invasive surgical approach with the aim of achieving an optimal cosmetic result. Reconstructive surgery for an osteoma is quite infrequent and reserved for patients with large central osteomas, such as big mandibular or maxillary lesions. In this regard, computer-assisted surgery guarantees better outcomes, providing the possibility of preoperative simulation of demolitive and reconstructive surgery

Dynamical friction of massive objects in galactic centres

Dynamical friction leads to an orbital decay of massive objects like young compact star clusters or Massive Black Holes in central regions of galaxies. The dynamical friction force can be well approximated by Chandrasekhar's standard formula, but recent investigations show, that corrections to the Coulomb logarithm are necessary. With a large set of N-body simulations we show that the improved formula for the Coulomb logarithm fits the orbital decay very well for circular and eccentric orbits. The local scale-length of the background density distribution serves as the maximum impact parameter for a wide range of power-law indices of -1 ... -5. For each type of code the numerical resolution must be compared to the effective minimum impact parameter in order to determine the Coulomb logarithm. We also quantify the correction factors by using self-consistent velocity distribution functions instead of the standard Maxwellian often used. These factors enter directly the decay timescale and cover a range of 0.5 ... 3 for typical orbits. The new Coulomb logarithm combined with self-consistent velocity distribution functions in the Chandrasekhar formula provides a significant improvement of orbital decay times with correction up to one order of magnitude compared to the standard case. We suggest the general use of the improved formula in parameter studies as well as in special applications.Comment: 22 pages, 28 figures, accepted by MNRA

Precision measurement of the neutrino velocity with the ICARUS detector in the CNGS beam

During May 2012, the CERN-CNGS neutrino beam has been operated for two weeks for a total of 1.8 10^17 pot in bunched mode, with a 3 ns narrow width proton beam bunches, separated by 100 ns. This tightly bunched beam structure allows a very accurate time of flight measurement of neutrinos from CERN to LNGS on an event-by-event basis. Both the ICARUS-T600 PMT-DAQ and the CERN-LNGS timing synchronization have been substantially improved for this campaign, taking ad-vantage of additional independent GPS receivers, both at CERN and LNGS as well as of the deployment of the "White Rabbit" protocol both at CERN and LNGS. The ICARUS-T600 detector has collected 25 beam-associated events; the corresponding time of flight has been accurately evaluated, using all different time synchronization paths. The measured neutrino time of flight is compatible with the arrival of all events with speed equivalent to the one of light: the difference between the expected value based on the speed of light and the measured value is tof_c - tof_nu = (0.10 \pm 0.67stat. \pm 2.39syst.) ns. This result is in agreement with the value previously reported by the ICARUS collaboration, tof_c - tof_nu = (0.3 \pm 4.9stat. \pm 9.0syst.) ns, but with improved statistical and systematic errors.Comment: 21 pages, 13 figures, 1 tabl